ITH options (mine)
Split time: 200
Process delay: 50
Inject delay : 3000
Insert delay: 500
Auto attach (checked)
Auto insert (checked)
Auto copy to clipboard (checked)
Auto suppress repetition (checked)
Remove 0 repetitions of each character
the rest is empty / unchecked
Missing characters is a h code problem but may be fixed by changing the font if your lucky.
VNR
I use VNR by aniclan:
Download, it has a bit of a load up time and can stall for a few minutes occasionally, but it has a lot of nice features for auto setting full screen and a nice overlay for translated text, and it has an h code database that can usually get an h code if needed.
Like ITH it requires ATLAS and the tool for ATLAS: Translation Aggregator for offline translation, and supports google and others for online translation.
After running it set it up in preferences, under Locations/Translators point it to the install path for ATLAS. Then under Translation/Translators, uncheck everything but ATLAS and under that Enable Japanese-English translation script. Then under Text to speech Disable TTS. I also have user contributed comments disabled under Features.
When you first attach to a game click options on the left side, Uncheck game text, Move the length slider half way or more, Zoom is the font size, Width is how far across the screen it will display the text.
ITH is better at a few VN's and is better for making h codes then VNR, VNR uses the ITH hook and acts almost identical except for the interface.
Read this
thread if have problems with VNR.