Only issue I have if they make Persona 5 on Vita would be its quality. To get a PS3/4 game of that size to run properly on the Vita they will have to trim it down considerably most likely, they might add a few things, but they will be forced to remove a lot also similar to Persona 3 on PSP where they had to strip it down to a visual novel style to run properly. The Vita is a lot more powerful then the PSP, but they will still have to cut the game back somewhat for it to run on the Vita.