Hello,
Most people tend to use a mix of Firefox and Chromium-based browsers.
Speaking as a hobbyist developer, I’ve noticed some differences. Firefox, for example, has historically used fewer resources (although that might not be as relevant in the latest version) but tends to struggle when you’ve got 80+ tabs open. On the other hand, Chrome uses more resources but still works perfectly, even with 500+ tabs loaded.
So, if your system has the resources to handle Chrome, it can take full advantage of them, though not in the most efficient way. Of course some forks will have different performance profiles.
That said, more nuance changes like Chrome dropping manifest v2 are worth noting. While I expect some forks to keep this this around, who knows how long that’ll last?