we are still looking for Anime with major romance content right ?
Karin
Lamune
Hatsukoi Limited
Da Capo
Saikano
Aishiteruze Baby
Amagami SS (well more like helping girls and they might fall for you but quite episodic ...)
Midori no Hibi
Akikan
Kobato
Noein (... it is .. complicated)
Akane-iro ni Somaru saka
Chaos Head (... quite psycholigical)
D.N.Angel (kinda like ... Kamikaze Kaito Jeanne but male lead and more romance)
Hoshizora e Kakeru Hashi (... was more into comedy and slice of life)
Final Approach (-"-)
This Ugly Yet Beautiful World
Maburaho
Onegai Twins
Oretachi no Tsubasa wa Nai
Angel Sanctuary (... well brother sister love but not the main focus of the story ... and kinda bloody)
Aoi Hana (sth about highschool girls love)
Strawberry Panic
Tales of ... series (sometimes have some implied romance)
Kanon (did we mentione that one already ?)
Zero no Tsukaima (... well at least some romantic moments

)
School Rumble (well if we are talking about failed romance under heaps of comedy -.-)
... i'm getting kinda dizzy and sometimes forget what was already mentioned or what the anime im thinking of went x_x (but re-watching them all would be a pain -.-)
hope it was/will be helpful